研究發表
2024
1.Huang CY, Tsai YH, Cheng YF, Wu PY, Chuang YC, Huang PY, Liu JS, CC Wu*, YF Cheng*. CRISPR/Cas9-mediated exon skipping to restore premature translation termination in a DFNB4 mouse model. Gene Therapy. In press. (*Corresponding author) (Cover story)
2.Hung SH, Chang AH, Cheng YF*, Lin HC, Chen CS*. Association of Young-Onset Dementia with Pre-Existing Peripheral Vestibular Disorders. J Alzheimers Dis. 2024;101(2):603-610. (*Corresponding author)
3.Yang TH, Chen CH, Cheng YF*, Lin HC, Chen CS*. Association of Peripheral Vestibular Disorder with Diabetes: A Population-Based Study. J Pers Med. 2024 Jul 19;14(7):768. (*Corresponding author)
4.Hung SH, Xirasagar S, Cheng YF*, Lin HC, Chen CS*. Association of Alzheimer's Disease With Peripheral Vestibular Disorder: A Case-Control Study. Laryngoscope. 2024 Jun 3. doi: 10.1002/lary.31558. Epub ahead of print. (*Corresponding author)
5.Yang TH, Chen YF, Cheng YF, Huang JN, Wu CS, Chu YC. Optimizing age-related hearing risk predictions: an advanced machine learning integration with HHIE-S. BioData Min. 2023 Dec 14;16(1):35
6.Hung SH, Xirasagar S, Dang LH, Viet-Nhi NK, Cheng YF*, Chen CS, Lin HC*. Prevalence of hearing loss, tinnitus, vertigo and sudden deafness among patients with polymyositis and dermatomyositis. Sci Rep. 2024 Mar 9;14(1):5774. (*Corresponding author)
7.Ho CW, Chen PY, Liao YT, Cheng YF*, Tsou HH, Liu TY, Liang KH. Uncovering the microbiome landscape in sashimi delicacies. Sci Rep. 2024 Mar 5;14(1):5454.
8.Yang TH, Xirasagar S, Cheng YF*, Chen CS, Lin HC*. Increased prevalence of peripheral vestibular disorder among patients with Fabry disease. Orphanet J Rare Dis. 2024 Mar 2;19(1):97. (*Corresponding author)
9.Yang TH, Xirasagar S, Cheng YF*, Chen CS, Lin HC. Increased prevalence of hearing loss, tinnitus and sudden deafness among patients with Sjögren's syndrome. RMD Open. 2024 Jan 19;10(1):e003308. (*Corresponding author)
2023
10.Hung SH, Xirasagar S, Dang LH, Chen YC, Cheng YF*, Lin HC, Chen CS. Trends in the incidence of peripheral vestibular disorders: a Nationwide population-based study. Front Neurol. 2023 Dec 12;14:1322199.
11.Huang TC, Liang KH, Chang TJ, Hung KF, Wang ML, Cheng YF, Liao YT, Yang DM. Structure-based approaches against COVID-19. J Chin Med Assoc. 2024 Feb 1;87(2):139-141.
12.Yang TH, Xirasagar S, Cheng YF*, Chen CS*, Lin HC*. Does peripheral vestibular disorder increase the risk of attempted suicide: A retrospective cohort study. J Affect Disord. 2023 Nov 15;341:12-16. (*Corresponding author)
13.Yang TH, Cheng YF, Chen CS, Lin HC. Increased prevalences of head and neck cancers in patients with Sjögren's syndrome. Head Neck. 2023 Nov;45(11):2874-2881.
14.Hung SH, Yang TH, Cheng YF*, Chen CS*, Lin HC*. Associations of Head and Neck Cancer with Hepatitis B Virus and Hepatitis C Virus Infection. Cancers (Basel). 2023 Sep 11;15(18):4510. (*Corresponding author)
15.Yang TH, Xirasagar S, Cheng YF*, Chen CS*, Chang WP*, Lin HC*. Trends in the incidence of head and neck cancer: A nationwide population-based study. Oral Oncol. 2023 May;140:106391. (*Corresponding author)
16.Yang TH, Chang AH, Cheng YF, Chen CS, Lin HC. Association of Chronic Otitis Media with Sjogren's Syndrome: A Case-Control Study. J Pers Med. 2023 May 27;13(6):903.
17.Hung SH, Yang TH, Cheng YF*, Chen CS*, Lin HC*. Association of Nasopharynx Cancer with Human Papillomavirus Infections. Cancers (Basel). 2023 Aug 13;15(16):4082. (*Corresponding author)
18.Lan WL, Chen CH, Chu YC, Cheng YF, Huang CY. Is There an Association between Concurrent Epstein-Barr Virus Infection and Sudden Hearing Loss?-A Case-Control Study in an East Asian Population. J Clin Med. 2023 Mar 1;12(5):1946.
19.Chen CH, Hung KF, Huang CY, Leong JL, Chu YC, Chang CY, Wang ML, Chiou SH, Cheng YF*. Is N -acetylcysteine effective in treating patients with coronavirus disease 2019? A meta-analysis. J Chin Med Assoc. 2023 Mar 1;86(3):274-281. (*Corresponding author)
20.Yang DM, Chang TJ, Hung KF, Wang ML, Cheng YF, Chiang SH, Chen MF, Liao YT, Lai WQ, Liang KH. Smart healthcare: A prospective future medical approach for COVID-19. J Chin Med Assoc. 2023 Feb 1;86(2):138-146
21.Cheng YF, Xirasagar S, Kuo NW, Lin HC. Tinnitus and risk of attempted suicide: A one year follow-up study. J Affect Disord. 2023 Feb 1;322:141-145.
2022
22.Cheng YF, Xirasagar S, Chen CS, Niu DM, Lin HC. Association of Fabry Disease with Hearing Loss, Tinnitus, and Sudden Hearing Loss: A Nationwide Population-Based Study. J Clin Med. 2022; 11(24):7396.
23.Lin HYH, Lai HS, Huang CY, Chen CH, Wu SL, Chu YC, Chen YF, Lai YH, Cheng YF*. Smartphone-bundled Earphones as Personal Sound Amplification Products in Adults with Sensorineural Hearing Loss. iScience. 2022 Nov 15;25(12):105436. (*Corresponding author)
24.Hung SH, Xirasagar S, Cheng YF*, Kuo NW, Lin HC*. Association of Chronic Kidney Disease with Prior Tinnitus: A Case–Control Study. J Clin Med. 2022; 11(24):7524. (*Corresponding author)
25.Cheng HL, Han JY, Chu YC, Cheng YF, Lin CM, Chiang MC, Wu SL, Lai YH, Liao WH. Evaluating the hearing screening effectiveness of active noise cancellation technology among young adults-A pilot study. J Chin Med Assoc. 2023 Jan 1;86(1):105-112.
26.Cheng HL, Han JY, Zheng WZ, Cheng YF, Chu YC, Lin CM, Chiang MC, Liao WH, Lai YH. Objective Signal Analysis for Investigating Feasibility of Active Noise Cancellation in Hearing Screening. Sensors (Basel). 2022 Sep 27;22(19):7329.
27.Lu YC, Tsai YH, Chan YH, Hu CJ, Huang CY, Xiao R, Hsu CJ, Vandenberge LH, Wu CC*, Cheng YF*. Gene therapy with a synthetic adeno-associated viral vector improves audiovestibular phenotypes in Pjvk mutant mice. JCI Insight. 2022 Oct 24;7(20):e152941 (*Corresponding author) (Cover story)
28.Chen YC, Chu YC, Huang CY, Lee YT, Lee WY, Hsu CY, Yang AC*, Liao WH*, Cheng YF*. Smartphone-based artificial intelligence using a transfer learning algorithm for the detection and diagnosis of middle ear diseases : a retrospective deep learning study. EClinicalMedicine. 2022 Sep 7;51(9):101543 (*Corresponding author)
29.Chen PY, Tsai CY, Wu JL, Li YL, Wu CM, Chen KC, Hwang CF, Wu HP, Lin HC, Cheng YF, Lo MY, Liu TC, Yang TH, Chen PL, Wu, C. C. Hearing Features and Cochlear Implantation Outcomes in Patients With Pathogenic MYO15A Variants: a Multicenter Observational Study. Ear Hearing. 2022 Jul-Aug;43(4):1198-1207
30.Chen JE, Chen YR, Wang HH, Niu DM, Cheng YF, Chen YJ. KMT2D-related disorder with a restricted spectrum distinct from Kabuki syndrome: a rare case report describing male twins in Taiwan and a literature review. Pediatrics & Neonatology. 2022 Jul 31:S1875-9572(22)00157-7. Online ahead of print.
31.Liang KH, Hung KF, Wang ML, Chang TJ, Cheng YF, Chiang SH, Chen MF, Liao YT, Chiou SH, Yang DM. SARS-CoV-2 vaccines in children and adolescents: Can immunization prevent hospitalization? J Chin Med Assoc. 2022 Jul 11. Epub ahead of print.
32.Huang PH, Xirasagar S, Chen JH, Cheng YF*, Kuo NW*, Lin HC*. Absence of Association of Tinnitus With Pre-existing Hypertension: A Population-based Study. Ann Otol Rhinol Laryngol. 2022 Aug 3:34894221115756. Epub ahead of print. PMID: 35923124. (*Corresponding author)
33.Leong JL, Chen CH, Huang CY, Cheng HL, Chu YC, Chang CY, Cheng YF*. Combination Therapy and Single-Modality Treatment for Acute Low-Tone Hearing Loss: A Meta-analysis with Trial Sequential Analysis. Brain Sci. 2022 Jun 12;(7):866. (*Corresponding author)
34.Chen CH, Huang CY, Cheng HL, Lin HYH, Chu YC, Chang CY, Lai YH, Wang MC, Cheng YF*. Comparison of personal sound amplification products and conventional hearing aids for patients with hearing loss: A systematic review with meta-analysis. EClinicalMedicine. 2022 Apr 7;46(4):101378. (*Corresponding author)
35.Huang H, Chen YF, Hsu CY, Cheng YF, Yang TH. Evaluating auditory brainstem response to a level-dependent chirp designed based on derived-band latencies. J Acoust Soc Am. 2022 Apr;151(4):2688.
36.Chen CH, Huang CY, Cheng HL, Lin HH, Chu YC, Chang CY, Lai YH, Wang MC, Cheng YF*. Smartphone-Enabled versus Conventional Otoscopy in Detecting Middle Ear Disease: A Meta-Analysis. Diagnostics. 2022 Apr 13;12(4):972. (*Corresponding author)
37.Hung SH, Xirasagar S, Kuang TMT, Chang WW, Cheng YF*, Kuo NW*, Lin HC*. Association of Age-Related Macular Degeneration with Prior Hyperthyroidism and Hypothyroidism: A Case-Control Study. J Pers Med. 2022 Apr 8;12(4):602. (*Corresponding author)
38.Lin HC, Xirasagar S, Wang CH, Cheng YF*, Yang TH*. Increased Risk of Major Depressive Disorder Following Tinnitus: A Population-Based Study. Front Neurol. 2022 Mar 21;13:836842. (*Corresponding author)
39.Ting KC, Chang CC, Huang CY, Chen YF, YF Cheng*. Are Electrocochleographic Changes an Early Sign of Cochlear Synaptopathy? A Prospective Study in Tinnitus Patients with Normal Hearing. Diagnostics. 2022 Mar 25;12(4): 802. (*Corresponding author)
40.Kuang TMT, Xirasagar S, Cheng YF, Kuo NW, Lin HC. Association of Primary Open-angle Glaucoma With Tinnitus: A Nationwide Population-Based Study. J Glaucoma. 2022 Apr 1;31(4):224-227.
41.Huang CY, Li SD, Tsia MH, Chen CH, Cheng YF*. The Impact of Acute Tinnitus on Listening Effort: A Study Based on Clinical Observations of Sudden Sensorineural Hearing Loss Patients. Int J Environ Res Public Health. 2022. Mar 19;19(6):3661 (*Corresponding author)
42.Huang CY, Cheng YF, Yang AC, Lin CJ., Leong PI, Hsueh CY. The moderating effect of personality traits on acute tinnitus sensation in idiopathic sudden sensorineural hearing loss. J Chin Med Assoc. 2022 Mar 11.
43.Kuang TMT, Xirasagar S, Lee WY, Cheng YF, Kuo NW, Lin HC. Absence of an Association between Macular Degeneration and Young-Onset Dementia. J Pers Med. 2022 Feb 16;12(2):291
44.Chang FL, Chen CH, Cheng HL, Chang CY, Leong JL, Chang YT, Cheng YF*, Liao WH*. Efficacy of Ventilation Tube Insertion with Palatal Repair for Otitis Media in Cleft Palate: Meta-Analysis and Trial Sequential Analysis. J Per Med. 2022 Feb 10;12(2):255. (*Corresponding author)
2021
45.Cheng YF, Xirasagar S, Yang TH, Kuo NW, Lin HC. Association of hearing loss with land transport accidents: a nationwide population-based study. Int J Audiol. 2021 Nov 12:1-5
46.Yang TH, Chu YC, Chen YF, Chen MY, Cheng YF, Wu CS, Huang HM. Diagnostic Validity of Self-Reported Hearing Loss in Elderly Taiwanese Individuals: Diagnostic Performance of a Hearing Self-Assessment Questionnaire on Audiometry. Int J Environ Res Public Health. 2021 Dec 15;18(24):13215
47.Cheng YF, Xirasagar S, Liu TC, Kuo NW, Lin HC. Ten-year trends in the incidence of microtia: a nationwide population-based study from Taiwan. Eur Arch Otorhinolaryngol. 2021 Nov;278(11):4315-4319
48.Hu CJ, Lu YC, Tsai YH, Lin PH, Lee YS, Yu IS, Lin SW, Liu TC, Hsu CJ, Yang TH, Cheng YF*, Wu CC*. Insights into phenotypic differences between humans and mice with p.T721M and other C-terminal variants of the SLC26A4 gene. Sci Rep. 2021 Oct 25;11(1):20983. (Corresponding author)
49.Chen CH, Lin HYH, Wang MC, Chang CY, Huang CY, Cheng YF*. Diagnostic Accuracy of Smartphone-based Audiometry for Hearing Loss Detection: A Meta‐analysis. JMIR Mhealth Uhealth. 2021 Sep 10;9(9):e28378. (*Corresponding author)
50.Chen CH, Huang CY, Lin HYH, Wang MC, Huang, Cheng YF*. Association of Sodium Thiosulfate with Risk of Ototoxic Effects from Platinum-based Chemotherapy: A Systematic Review and Meta-analysis. JAMA Network Open. 2021 Aug 2 ;4(8):e2118895. (*Corresponding author)
51.Ridge SE, Chari DA, Kozin ED, Remenschneider AK, Adunka OF, Aristegui M, Chang WT, Cheng YF, et al. International Survey of Operative Practices for Otologists and Neurotologists During the COVID-19 Crisis. Otol & Neurotol. 2021 Sep 1;42(8), 1275–1284.
52.Hsueh CY, Huang CY, Yang CF, Chang CC, Lin WS, Cheng HL, Wu SL, Cheng YF*, Niu DM*. Hearing characteristics of infantile‑onset Pompe disease after early enzyme‑replacement therapy. Orphanet J Rare Dis. 2021 Aug 5;16(1):348 (*Corresponding author)
53.Cheng YF, Xirasagar S, Yang TH, Wu CS, Kuo NW,Shia BC, Lin HC. Risk of Early-Onset Dementia Among Persons with Tinnitus – A Retrospective Case-Control Study. Sci Rep. 2021 Jun 28;11(1):13399.
54.Lin HC, Cheng YF, Yang TH. Stroke and chronic rhinosinusitis: a look backward and forward. Pol Arch Intern Med. 2021 Apr 29;131(4):322-323. (Invited Editorial)
55.Lin HC†, Xirasagar S, Wang CH†, Cheng YF†, Liu TC, Yang TH. A Nationwide Population-Based Study on the Association between Land Transport Accident and Peripheral Vestibular Disorders. Int J Environ Res Public Health. 2021, 18(12), 6570 (†Equal contribution)
56.Hu CJ, Lu YC, Yang TH, Chan YH, Tsai CY, Yu IS, Lin SW, Liu TC, Cheng YF*, Wu CC, Hsu CJ. Toward the Pathogenicity of the SLC26A4 p.C565Y Variant Using a Genetically Driven Mouse Model. Int J Mol Sci. 2021 Mar; 22(6): 2789 (*Corresponding author)
57.Cheng YF, Xirasagar S, Kuo NW, Chung SD, Lin HC. Association of Erectile Dysfunction with Tinnitus: A Nationwide Population-based Study. Sci Rep. 2021 Mar 26;11(1):6982.
58.Yang TH, Xirasagar S, Cheng YF, Wang CH, Lin HC. Increased Risk of Injury Following a Diagnosis of Vertigo: A Population-based Study. Laryngoscope. 2021 Mar 18.
59.Cheng YF, Xirasagar S, Yang TH, Wu CS, Kao YW, Lin HC. A Population-Based Case-control Study of the Association between Cervical Spondylosis and Tinnitus. Int J Audiol. 2021 Mar;60(3):227-231.
60.Yang TH, Xirasagar S, Cheng YF, Kuo NW, Lin HC. Association of Cervical Spondylosis With Peripheral Vertigo: A Case-Control Study. Laryngoscope. 2021 Feb;131(2):E625-E630
61.Liao WH, Cheng YF, Chen YC, Lai YH, Lai F, Chu YC. Physician decision support system for idiopathic sudden sensorineural hearing loss patients. J Chin Med Assoc. 2021 Jan 1;84(1):101-107.
2020
62.Chen CH, Huang CY, Chang CY, Cheng YF*. Efficacy of Low-Level Laser Therapy for Tinnitus: A Systematic Review with Meta-Analysis and Trial Sequential Analysis. Brain Sci. 2020 Dec 2;10(12):E931. (*Corresponding author)
63.Chen YC, Huang CY, Lee YT, Wu CH, Chang SK, Cheng HL, Chang PH, Niu DM*, Cheng YF*. Audiological and otologic manifestations of glutaric aciduria type I. Orphanet J Rare Dis. 2020 Dec 1;15(1):337. (*Corresponding author)
64.Yang TH†, Xirasagar S; Cheng YF†, Wu CS; Kao YW, Lin HC. A Nationwide Population-Based Study on the Incidence of Parapharyngeal and Retropharyngeal Abscess-A 10-Year Study. Int J Environ Res Public Health. 2021 Jan 25;18(3):1049. (†Equal contribution)
65.Lin HYH, Chu YC, Lai YH, Cheng HL, Lai FP, Cheng YF*, Liao WH. A Smartphone-Based Approach to Screening for Sudden Sensorineural Hearing Loss: A Cross-sectional Validity Study. JMIR Mhealth Uhealth. 2020 Nov 11;8(11):e23047. (*Corresponding author)
66.Cheng YF, Tsai YH, Huang CY, PC Chang, YH Lee, Lu YC, Hsu CC, Wu CC. Generation and pathological characterization of a transgenic mouse model carrying a missense PJVK mutation. Biochem Biophy Res Commun. 2020 Nov 19;532(4):675-681
67.Hu CJ, Lu YC, Tsai YH, Cheng HY, Takeda H, Huang CY, Xiao R, Hsu CJ, Tsai JW, Vandenberghe LH, Wu CC, Cheng YF*. Efficient in utero gene transfer to the mammalian inner ears by the synthetic adeno-associated viral vector Anc80L65. Mol Ther Methods Clin Dev. 2020 Jun 24;18:493-500. doi: 10.1016/j.omtm.2020.06.019. eCollection 2020 Sep 11. (*Corresponding author) (Cover Story)
68.Cheng YF, Xirasagar S, Yang TH, Wu CS, Kao YW, Shia BC, Lin HC. Increased Risk of Tinnitus Following a Trigeminal Neuralgia Diagnosis: A One-year Follow-up Study. 2020 May 6;21(1):46. J Headache Pain. 2020 May 6;21(1):46.
69.Chen YC, Huang CY, Kuo YJ, Cheng HL, Cheng YF*, Liao WH. Developing a novel meatal areolar tissue autograft for minimally invasive tympanoplasty. J Chin Med Assoc. 2020 Oct;83(10):956-961 (*Corresponding author)
70.Huang CY, Tsai YH, Tsai YC, Chan YC, Chiou SH, Wu CC, Cheng YC*. Establishment of an induced pluripotent stem cell (iPSC) line from a 7-year-old male patient with profound hearing loss carrying c.235delC in GJB2 gene. Stem Cell Research, 2020 May;45:101795. (*Corresponding author)
71.Yang TH, Xirasagar S; Cheng YF, Wu CS; Kao YW, Shia BC, Lin HC. Malignant Otitis Externa Is Associated with Diabetes: A Population-based Case-control Study. Ann Otol Rhinol Laryngol. 2020 Jun;129(6):585-590
72.Yang TH, Xirasagar S, Cheng YF, Wu CS, Kuo NW, Lin HC. Peripheral Vestibular Disorders: Nationwide Evidence From Taiwan. Laryngoscope. 2021 Mar;131(3):639-643. Epub 2020 Jul 4.
73.Yang TH, Xirasagar S, Cheng YF, Wu CS, Kao YW, Shia BC, Lin HC. Association of cervical spondylosis with obstructive sleep apnea. Sleep Med. 2020 Jul;71:54-58.
74.Yang TH, Xirasagar S, Cheng YF, Wu CS, Huang CC, Lin HC. Association between Pioglitazone Use and Head and Neck Cancer: A Population-based Case-Control Study. Head Neck. 2020 Apr;42(4):653-659.
2019
75.Cheng YF, Chan YH, Hu CJ, Lu YC, Fujioka M, Okano H, Hsu CJ, Chang KH, Wu CC. Generation of a human iPS cell line (CGMH.SLC26A4919-2) from a Pendred Syndrome patient carrying SLC26A4 c.919-2A>G splice-site mutation. Stem Cell Res. 2019 Oct;40:101524.
76.Cheng YF, Yang TH, Wu CS, Lin HC. A Population-based Time Trend Study in the Incidence of Malignant Otitis Externa. Clin Otolaryngol. 2019 Sep;44(5):851-855
77.Shen J, Oza AM, Del Castillo I, Duzkale H, Matsunaga T, Pandya A, Kang HP, Mar-Heyming R, Guha S, Moyer K, Lo C, Kenna M, Alexander JJ, Zhang Y, Hirsch Y, Luo M, Cao Y, Wai Choy K, Cheng YF, Avraham KB, Hu X, Garrido G, Moreno-Pelayo MA, Greinwald J, Zhang K, Zeng Y, Brownstein Z, Basel-Salmon L, Davidov B, Frydman M, Weiden T, Nagan N, Willis A, Hemphill SE, Grant AR, Siegert RK, DiStefano MT, Amr SS, Rehm HL, Abou Tayoun AN; ClinGen Hearing Loss Working Group.Consensus interpretation of the Met34Thr and Val37Ile variants in GJB2 by the ClinGen Hearing Loss Expert Panel. Genet Med. 2019 Nov;21(11):2442-2452.
78.Meng XK, Murali S, Cheng YF, Lu J, Hight A, Kanumuri V, Brown MC, Holt JR, Lee DJ, Edge ASB. Increasing the Expression Level of ChR2 Enhances the Optogenetic Excitability of Cochlear Neurons. J Neurophysiol. 2019 Nov 1;122(5):1962-1974
79.Wu CC, Tsai CY, Lin YH, Chen PY, Lin PH, Cheng YF, Wu CM, Lin YH, Lee CY, Erdenechuluun J, Liu TC, Chen PL, Hsu CJ. Genetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population. Genes. 2019 Oct 1;10(10).
80.Chan YH, Liu TC, Liao CK, Cheng YF, Tsai CH, Lu YC, Hu CJ, Lin HJ, Lee YL, Wu CC, CJ Hsu. Consumption of betel quid contributes to sensorineural hearing impairment through arecoline-induced oxidative stress. Sci Rep. 2019 Oct 10;9(1):14554
